Infection is one of the most common occurring issues in an individual.
Diseases caused by infections hamper the immune system of an individual. To
modulate the immune system, immunomodulatory drugs work by either stimulating or
suppressing the immune system. Several drugs like levamisole and azathioprine are
available in the market today to overcome various infections. But an alternative is
required to overcome the drug resistance and other side effects associated with these
available drugs. To tackle these problems, many plant-based immunomodulators are
being explored and have proven to be beneficial against these infections. This chapter
focuses on the mechanism of action and application of natural immunomodulators like
Curcumin, Resveratrol, and Genistein on various infections. The primary goal of this
chapter is to understand the role of natural immunomodulators in the body for various
infections and related disease conditions. With the help of findings, one can conclude
that all-natural immunomodulators have areas that need attention, including their
therapeutic risk-benefit ratio and their target binding affinity for various infections.
However, further investigations into these drugs are necessary for a clear understanding
to maximize their clinical applications
Keywords: Natural Immunomodulators, Antimicrobial, Antibacterial, Antiviral, Antiparasitic, Ayurveda, Curcumin, Genistein, Immunosuppressants, Immunostimulants, Infection, Resveratrol.