Since algae are simple organisms that contain chlorophyll, they can be found anywhere on earth where they can use light for photosynthesis. Although pool-type open systems are generally used, closed photobioreactors are also used in the cultivation of algae. The low investment and operating costs of the outdoor pools made the system preferable in the industry. However, the difficulty of controlling the production conditions and the risk of contamination appears as the disadvantages of the system. It is necessary to compare fundamental aspects such as effective use of light in large-scale culture systems, temperature, hydrodynamic balance in algae culture, and maintaining the continuity of the culture. The ideal growth of each algae species takes place in culture media with its specific conditions. For example, Spirulina grows best at high pH and bicarbonate concentration, Chlorella in nutrient-rich media, and Dunaliella salina at very high salinity.