Signaling pathways are important tools for regulating cellular life cycles
such as growth and replication. Any external influences may cause a disturbance in
signaling, causing an uncontrolled division of cells causing cancer. Many receptors
such as EGFR are active in signaling for cancer, which can be targeted to show potent
anticancer activity.
Keywords: Chromosomal instability, Microsatellite instability, Pathways, Signalling.