Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery Systems Part II

Self-Nano/Micro Emulsified Drug Delivery System

Author(s): Vishal Trivedi* and Jiyauddin Khan

Pp: 73-93 (21)

DOI: 10.2174/9789815036541122010007

* (Excluding Mailing and Handling)

Abstract

A self-emulsifying drug delivery system is defined as a mixture of isotropic substances such as oil and surfactant solvents/co-solvents, which is used for the improvement of the oral drug delivery system. The oral drug delivery system consists of soft and hard gelatin capsules. They are stable O/W emulsion preparations. There are several types of parameters used in this process. The utilisation of herbal medicine has been gaining popularity of late. Herbal drugs are also used in self-emulsion drug delivery systems due to their isotropic thermodynamic property. The lipophilic nature of this formulation could solve the problem of poor solubility of drugs. The bioavailability of poorly soluble drugs is determined by the drug dissolution process. Prodrug process is used to improve bioavailability.


Keywords: Bioavailability, Herbal drugs, Oral dosage form, SEDDS and SMEDDS.

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