Advances in Organic Synthesis

Volume: 2

Enantioselective Electrophilic Fluorination: The Complete Story

Author(s): C. Audouard, J. -A. Ma and D. Cahard

Pp: 431-461 (31)

DOI: 10.2174/978160805198410602010431


Progress in the field of enantioselective electrophilic fluorination during the past eighteen years resulting from fascinating research conducted by twelve international groups is reviewed. Two complementary strategies for the synthesis of enantiopure fluorine-containing molecules currently define state-of-the-art in this area. The use of chiral, non-racemic fluorinating agents is the most general approach while catalytic methods using either transition-metal catalysts or organocatalysts apply to specific substrates.

Related Journals
Related Books
© 2024 Bentham Science Publishers | Privacy Policy