Quercetin, A Flavonoid with Remarkable Anticancer Activity

Pp: 40-74 (35)

* (Excluding Mailing and Handling)

Cancer is the second leading cause of death globally and is responsible for

about 10 million deaths per year. Several therapeutic options are available currently to

treat this deadly disease by targeting various enzymes, receptors, signaling pathways,

and nucleic acids. Development of drug resistance, new oncogenic proteins, and

recurrence demands sustained discovery of new therapeutic options. Flavonoids are a

class of plant polyphenols consisting of 15 carbon skeletons with two benzene rings

linked together to a heterocyclic pyrone ring. So far, more than 4,000 flavonoids of

different types have been discovered from nature. Flavonoids exhibit several biological

activities, including cancer. Quercetin (QCT) is one of the most studied flavonoids that

belongs to the flavones subclass. In the recent five years, immense efforts have been

made in discovering the anticancer aspect of QCT. This book chapter summarizes the

anticancer activities of QCT on various cancer cells (in vitro) and tumors (in vivo)

reported in the last five years.

Keywords: Anticancer, Cancer, Flavonoids, Natural Products, Quercetin.

Cite as

Current Chinese Science

Anti-Cancer Agents in Medicinal Chemistry

Current Computer-Aided Drug Design

Current Bioactive Compounds

Current Medicinal Chemistry

Current Topics in Chemistry

The Natural Products Journal

Current Catalysis

Current Chinese Chemistry

Combinatorial Chemistry & High Throughput Screening

A Journey Through Water: A Scientific Exploration of The Most Anomalous Liquid on Earth

Advances in Mathematical Chemistry and Applications

Advances in Mathematical Chemistry and Applications Volume 1 (Revised Edition)

Advances in Organic Synthesis

DOI https://doi.org/10.2174/9789815040586122090005	Print ISSN 1574-0897
Publisher Name Bentham Science Publisher	Online ISSN 2212-3997

Frontiers in Natural Product Chemistry