Artemisinin Analogues as a Novel Class of Antimalarial Agents: Recent Developments, Current Scenario and Future Perspectives

The comprehensive chronological advancement and statistical account of

the recent developments and current scenario on antimalarial chemotherapy, in

particularly, based on various types of artemisinin analogues and their potential as

antimalarial agents have been schematically presented in this book chapter. These

studies had compared efficacies of various semi-synthetic artemisinin analogues with

that of standard reference drug artemisinin, β-Arteether and various other anti-malarial

drugs. Thus, this book chapter highlights the recent advancements and historical

developments observed in the medicinal chemistry of artemisinin since its discovery

during the past 49 years (1971-2020). Hence, this book chapter will serve as first-hand

information on artemisinin-based antimalarial peroxides to organic and medicinal

chemists, as well as biologist/pharmacologists working on anti-malarial drug discovery

and development.

Keywords: Antimalarial peroxides, Arteether, Artemisinin, Artesunate, Malaria, Multi-drug Resistant.

Cite as

Current Drug Delivery

Current Bioactive Compounds

Current Drug Safety

Reviews on Recent Clinical Trials

Drug Delivery Letters

Recent Advances in Drug Delivery and Formulation

Recent Advances in Anti-Infective Drug Discovery

Drug Metabolism and Bioanalysis Letters

Applied Drug Research, Clinical Trials and Regulatory Affairs

Current Drug Targets - Inflammation & Allergy

A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems

Angiogenesis & Therapeutic Targets In Cancer

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Chemoinformatics: Directions Toward Combating Neglected Diseases

Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms

DOI https://doi.org/10.2174/9789815036879122110005	Print ISSN 1574-0889
Publisher Name Bentham Science Publisher	Online ISSN 2212-1064

Frontiers in Drug Design and Discovery