Medical Applications of Beta-Glucan

Beta Glucan and Lyme Disease (lD)

Author(s): Betül Gürünlü

Pp: 115-120 (6)

DOI: 10.2174/9789815039238122010014

* (Excluding Mailing and Handling)

Abstract

Lyme disease (LD) is an insect-borne infectious disease caused by
spirochetes-spiral shaped-flexible bacteria titled as Borrelia burgdorferi, has been
rapidly growing in United States, Europe, and Asia. During Lyme disease, Borrelia
burgdorferi causes the release of pro-inflammatory type cytokines such as interleukin
(IL-1), and T-helper cell-derived cytokines stimulating inflammation. Lyme disease
causes a wide scale of disorders on the human body i.e. skin, heart. It builds a broad
scale of problems such as arthritic symptoms at joints, nervous system problems,
bacterial infection, flu-like symptoms [1]. It creates a systemic problem for the host,
which can include, and Experimental studies showed that treatment with antibiotics
with 3-6 beta-glucan creates a synergistic effect on bacterial and viral infections due to
Lyme-Multiple Systemic Infectious Disease Syndrome (MSIDS) [2]. In this minireview,
the therapeutical effect of beta glucan on Lyme disease is examined in detail. 


Keywords: β-glucan, Beta Glucan, Lyme Disease.

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