The state of individual physical well-being, which is considered as health, can be affected by the physical environment, as well as the factors going on within an individual. Poor health requires continuous monitoring for the individuals, and the process needs monitoring in hospitals or individuals’ homes. Furthermore, the recorded health data should be analyzed by specialists to be prepared for further processing, such as artificial intelligence (AI), using the latest environment of technology. Many healthcare applications considering AI have been studied, especially in cancer diagnosis and treatment, in recent years. Deep learning, expressed as the future of healthcare, is driven by increased computational power and huge datasets. In this chapter, an introduction to machine learning (ML), AI, and deep learning in healthcare will be studied.