Curcuma longa, due to its broad scope of remedial possibilities, is still
utilized as a diet-based remedy against diabetes mellitus and diabetic intricacies by
legitimately connecting with various cellular pathways that incite diabetes mellitus
pathogenesis. This chapter investigates the general valuable impacts of Curcuma longa
on diabetes mellitus and its related complications based on experimental studies.
Alongside clarifying the useful facts of Curcuma longa, it might be helpful to consider
those cellular pathways which directly relate to diabetes. The possible mechanism of
action of Curcuma longa as anti-hyperglycemic considered inhibition of lipid
peroxidation, starch using compounds, transcriptional compounds, and activation of
antioxidant enzyme capacity. Subsequently, Curcuma longa shows its antidiabetic
restorative impacts by expanding insulin affectability, securing β-cells of pancreatic
islets, diminishing fat accumulation, reducing oxidative stress, or enhancing glucose
take-up by the tissues. Other than this, Curcuma longa, likewise, shows defensive
impacts against a few diabetic-linked complications, prominently diabetic cataracts,
and kidney function, along with the antioxidant agents. Taking everything into account,
this work recommends that Curcuma longa help in treating diabetes and complications
that occur due to diabetes; however, tolerant advising is also necessary as directing
power to achieve diet-based treatment if there should be an occurrence of diabetes. In this chapter, we discuss basic and clinical proof of Curcuma longa's potential for
diabetes mellitus treatment mainly due to its hypoglycemic, antioxidant, and antiinflammatory
qualities.
Keywords: Antioxidative, Curcuma Longa, Diabetes Mellitus.
