In the recent past, dendrimer based nano-devices have become an attractive
center for medicinal chemists as a targeted drug delivery carrier. It is promising to
specifically manipulate both molecular weight and chemical composition of dendrimers
by regulating dendrimer synthesis, and thereby allowing predictable tuning of their
biocompatibility and pharmacokinetics. The myriad properties and functions of
dendrimers provide plenty of opportunities in this regard. Presently, the fields of
oncology, infectious disease, cardiovascular diseases, ocular disease, etc. need
biodegradable polymers, macromolecules based formulations to improve the safety and
efficacy of different therapeutics. Dendrimer has been extensively used for treating
disorders even for anti-viral therapeutics, including AIDS-HIV . The present book
chapter reports the role of dendrimers in drug delivery systems for various agents, in
biology and medical science. Additionally, it covers the fundamentals of dendrimeric
properties and types for cancer diagnosis and other therapy.
Keywords: Dendrimers, Drug delivery, PAMAM, Therapeutics.
