The global pandemic situation of COVID-19 has drawn the attention of
various health care professionals. Several preclinical or clinical investigations have
been explored; however, effective management of COVID-19 has not been found yet.
The infection to death ratio related to COVID-19 varies in different countries, yet
endangering human survival. Therefore, at present, prevention from SARS-CoV-2
infection appears promising in limiting the spread of the disease. The susceptibility of
different individuals varies extensively in a demographic distribution. It has been found
that patients with cardiovascular or metabolic disorders, smoking habits, and health
care professionals have a higher susceptibility towards SARS-COV-2 infection.
Therefore, it becomes mandatory to spread awareness to the people who are at higher
risk. After COVID-19 infection, the occurrence of several complications may be lifethreatening.
Thus, this review has summarized the information regarding the
susceptibility of people towards COVID-19 disease and disabling/life-threatening
conditions after getting infected from COVID-19 disease.
Keywords: ACE, COVID-19, Diabetes mellitus, Hypertension, Risk factors,
SARS-CoV-2.