Many COVID-19 patients die not just because of the virus but also due to
the patient’s own immune system responding in an exaggerated manner called
“Cytokine Storm”. This stormy strong immune response not only just kills the virus but
also kills the patients. The interaction of COVID-19 with the immune system is poorly
understood. Recently, some studies have indicated the alteration of innate and adaptive
immune signalling pathways after COVID-19 infection. Thus, in this chapter, we have
compared the normal immune signalling pathways with COVID-19 altered immune
signalling pathways, which will help the researchers in the designing and development
of specific drugs or vaccines against this virus.
Keywords: Adaptive immune system, COVID-19, Innate immune system.