Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China, affecting millions of peoples worldwide, and was declared as a global health emergency by the World Health Organization (WHO). This infection is extremely transmittable from humans to humans due to its long incubation period (as compared to other viruses of the same category), which results in asymptomatic carriers. The complete knowledge regarding this virus is still unclear and various studies are being conducted worldwide. Till now, no vaccines or specific drugs are available for its prevention and treatment. However, various classes of drugs are repurposed for their treatment and many new drugs and vaccines are under development. This chapter provides brief information related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) along with its diagnosis, prevention, and treatment strategies.