This chapter reports advances in synthetic methodologies employing chiral
auxiliaries for the stereoselective synthesis of biologically active natural molecules.
Derivatives of naturally occurring compounds such as amino acids, carbohydrates, and
terpenes, chiral auxiliaries have been described as an essential aid for the construction
of highly complex molecules. Among these auxiliaries, we highlight those of Evans,
Corey, Yamada, Enders, Oppolzer, Kunz, Meyers, and Schöllkopf, whose contributions
led to a remarkable progress in asymmetric synthesis in the last decades and continue
to bring advances until the present day.
Keywords: Asymmetric Synthesis, Biologically Active Compounds, Chiral
Auxiliaries, Corey’s Chiral Auxiliary, Evans’ Oxazolidinones, Enders, Kunz,
Meyers, Oppolzer, Schöllkopf, Yamada.
