The electromagnetic (EM) interference is one of the major issues in EM wave applications. To prevent electronic devices from the EM wave interference, there is a need to find novel materials for shielding the EM wave interference. In this chapter, we discussed the EM wave interference and the effective EM interference parameters to find the strength of shielding. The chapter contains the mechanism and some derived materials reported by the various scientists. The materials are classified as ferrites, composites, and carbon-based materials. Herein, some other interesting materials like ferrites and conducting polymer composites were discussed to shield the EM interference.