Diabetes mellitus is a complex metabolic disorder affecting more than 330 million people around the globe. Diabetes mellitus is identified as the fifth leading cause of death worldwide and causes various complications. The prevalence of diabetes mellitus is rising substantially from worldwide. Over the past few years, the global burden of diabetes mellitus has enlarged 382 million and this count may increase in the future. Cardiovascular disease is a group of numerous diseases such as heart failure, cardiomyopathy, congenital heart disease, coronary heart disease etc. causes severe health complications to the affected patients. The deposition of lipid particles inside the arteries can cause clot and favor for the progression of cardiovascular diseases which led to damage to the function of vital organs. Several risk factors are shared with the development of cardiovascular diseases include smoking, alcohol, stress, insufficient physical activity, poor diet, high blood pressure, high lipid profile, diabetes mellitus can greatly advance the risk of cardiovascular disease. Chest x ray, electrocardiogram, stress test, echocardiogram, holter monitoring, coronary angiogram, blood sugar test, lipid profile, investigations are used to detect the progression of cardiovascular disease in diabetic patients. Cardiovascular disease in diabetes mellitus can be prevented through lifestyle modification counseling and regular medication adherence and advance diagnostic and therapeutic management could reduce the progression of cardiovascular disease among diabetic patients.