This paper addresses the actual role of CSF in the physiology and
ethiopathogeny of mental disorders as schizophrenia, schizoaffective disorder and
bipolar disorder. Several decades ago the observation that the enlargement of
ventricular size was associated with a clinical diagnosis of schizoaffective illness was
reported [1] by first time.
Changes in the volume of the cerebral ventricles and therefore the content of the liquid
cephalous spinal far beyond the daily physiological variations, are already known in
mental disorders, but have only been to date more a curious object of in-depth studies
for various reasons. Usually it pays more attention to alterations of the nervous tissue in
which volumetric changes are observed in the ventricles. The finding that the melanin
molecule has the amazing ability to transform light energy into chemical energy
through the dissociation of the molecule of water, such as chlorophyll in plants; the old
dogma that the source of energy of the Central nervous system (CNS) is through blood
vessels break into a thousand pieces. We now know that the real source of energy of
the CNS is the visible and invisible light and the transducer per excellence is melanin,
and whose perfect substrate is water.
It is, therefore, that the CNS of all mammals has a repeating pattern invariably to be
coated inside and out by the CSF that is 99% water, which ensures that the energy
substrate source, water for all practical purposes, is constantly in contact with neurons.
The brain caesuras allow water getting as much as possible to the most recondite places
of the brain. Thereby the source of energy of CNS are the ventricles and subarachnoid
space, therefore, the changes in volumetric characteristics of this anatomic regions
must be interpreted as significant alterations in generation and distribution of chemical
energy.
Keywords: CSF, Melanin, Mental Illness, Ventricle size, Volume.