Abstract
This chapter is a brief review of the mechanistic aspects of drug action and discusses the concepts of receptors and drug receptor interactions critical for pharmacological responses of drugs. After study of this chapter, students will be able to: • Discuss about receptors from historical perspectives • Explain the mechanistic principles of drug action in light of receptors • Summarize different theories of drug action such as: - Occupancy Theory - Rate Theory - Induced-Fit Theory - Macromolecular Perturbation Theory - Occupation-Activation Theory of “Two-State” Model • Understand drug receptor interactions
Keywords: Affinity, Agonist, Antagonist, Drug receptor interaction, Efficacy, Intrinsic activity, Partial agonist, Receptor, Theories of drug action.
Related Journals
Current Chinese Science
Anti-Cancer Agents in Medicinal Chemistry
Current Computer-Aided Drug Design
Current Bioactive Compounds
Current Medicinal Chemistry
Current Topics in Chemistry
The Natural Products Journal
Current Catalysis
Current Chinese Chemistry
Combinatorial Chemistry & High Throughput Screening
Related Books
A Journey Through Water: A Scientific Exploration of The Most Anomalous Liquid on Earth
Advances in Mathematical Chemistry and Applications
Advances in Mathematical Chemistry and Applications
Advances in Mathematical Chemistry and Applications Volume 1 (Revised Edition)
Advances in Organic Synthesis
Advances in Organic Synthesis
Advances in Organic Synthesis
Advances in Organic Synthesis
Advances in Organic Synthesis
Advances in Organic Synthesis