Viruses are related to 15-20% of human cancers worldwide. Many studies
focused on clarifying the molecular mechanisms and genetic alterations caused by
oncogenic viruses. Among different oncoviruses, human papillomaviruses (HPVs) are
small, non-enveloped, double-stranded DNA viruses, which can infect mucosal or
cutaneous epithelia. Many HPVs have been classified as low-risk viruses associated
with benign warts in the general population. Other HPVs entitled as the high-risk HPV
types cause several important human cancers including cervical cancer, other
anogenital cancers and head and neck tumors. A general description of HPV types and
their association with different disorders are presented in this chapter.
Keywords: Cancer, Genome, Human papillomavirus.Cancer, Genome, Human papillomavirus.
