A wide array of syndromes reported in the literature have significant impact
on the craniofacial complex, with great influence on the facial aspect, which is usually
typical of each syndrome. For this reason, this chapter refers to these disorders as
“syndromes with unusual facies”, as described in the classical book of Gorlin et al.,.
Affecting the craniofacial complex, these syndromes also often have significant
implications for dental treatment and affected individuals may have peculiar dental
needs.
Keywords: Autosomal dominant, Autosomal recessive, Craniofrontonasal
dysplasia, De Lange syndrome, Dental care, Frontonasal dysplasia, Fronto-faci-
-nasal dysplasia, Kabuki syndrome, Mobius syndrome, Opitz GBBB syndrome,
Robinow syndrome, Tooth abnormalities, X-linked.
