This chapter is a brief overview of the burden of neurodegenerative diseases,
notably Alzheimer’s disease, on society, the short falls of current drug therapies and
emphasis on the reasons to increase our efforts in developing regenerative medicinebased
stem cell therapeutics. The chapter further provides caution on unsettled
translational concerns that are necessary to settle before proceeding with this
innovative treatment to the clinic, in addition to highlighting the promising basic strides
made in stem cell therapy of neurological disorders.
