This chapter presents a synthesis of data regarding iatrogenic injuries of the
liver, gallbladder and pancreas. For each of these organs, medical drug-induced lesions
are presented. The second part of the chapter includes the consequences of diagnostic
and/or therapeutic interventions for the above-mentioned organs. The liver is the
second most common organ involved in drug effects, following the skin. Its destruction
can be an indication for transplantation. The hepatic disorders include metabolic
disturbances, cholestasis, hepatitis, cirrhosis and risk of malignancy. The biliary
channels can be injured during open surgical interventions or laparoscopic
cholecystectomy, leading to fistulae, peritonitis, bilirrhagia and even death. Endoscopic
retrograde cholangiopancreatography (ERCP) can be associated with local
complications, such as pancreatitis and cholangitis, but pneumothorax,
pneumomediastinum and pneumoretroperitoneum are also encountered in rare cases.
Keywords: Adverse drug reaction, Allergy, Bilirrhagia, Cholangiopancreatography,
Cholecystectomy, Cholestasis, Cirrhosis, Gallbladder, Hematoma,
Hepatitis, Hepatocellular carcinoma, Hepatoportal sclerosis, Iatrogenic, Liver,
Pancreas, Pancreatitis, Peritonitis.
