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Precision Oncology in the Era of Biotechnology

Journal: Current Cancer Therapy Reviews
Guest editor(s): Dr. Mazhar Al-Zoubi Yarmouk University, Irbid, Jordan
Co-Guest Editor(s): Prof. Raed Al-Zoubi University Ferhat Abbas of Setif, Sétif, Algeria
Submission closes on: 27th March, 2027

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Impact Factor Current: 0.9
5 - Year: 0.8
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Introduction

The convergence of biotechnology innovations and precision medicine is transforming cancer care. Advanced biotechnological tools—including next-generation sequencing, CRISPR-based technologies, AI-driven diagnostics, engineered therapeutics (CAR-T, TCR-T, antibody-drug conjugates), and multi-omics profiling—are enabling unprecedented tumor characterization and personalized treatment strategies. This thematic issue will explore how biotechnology is reshaping precision oncology from bench to bedside, addressing diagnostic innovations, therapeutic breakthroughs, clinical implementation challenges, and future directions in making precision oncology accessible and effective for all patients.

Keywords

Precision Oncology, Biotechnology, Immunotherapy, Biomarkers, Next-Generation Sequencing, CRISPR, CAR-T Therapy, Personalized Medicine

Sub-topics

  • DNA analysis for early detection and monitoring
  • Single-cell sequencing and spatial transcriptomics
  • AI applications in biomarker discovery and diagnostics
  • CAR-T, CAR-NK, and tumor-infiltrating lymphocytes (TILs)
  • Next-generation antibody-drug conjugates
  • CRISPR and gene editing approaches in cancer therapy
  • MRNA-based cancer vaccines and immunotherapies
  • Molecular tumor boards and clinical decision-making in precision oncology
  • Overcoming therapeutic resistance through precision approaches