Introduction
Phosphine compounds have emerged as versatile agents in medicinal chemistry, offering unique structural and electronic properties that enable diverse biological applications. This thematic issue explores the expanding role of phosphines in drug design, therapeutic delivery, and bioinorganic mechanisms. From their use as ligands in metal-based drugs to their potential in anticancer, antimicrobial, and antioxidant therapies, phosphine derivatives are gaining attention for their tunable reactivity and biocompatibility. Recent advances in synthetic strategies and mechanistic understanding have opened new avenues for their integration into targeted therapies and diagnostic tools. By bringing together interdisciplinary research, this issue aims to highlight the innovative contributions of phosphine chemistry to modern medicine and inspire future developments in this promising field.
Keywords
Phosphine, metals, cancer, delivery, inhibitors, drugs
Sub-topics
- Synthetic Strategies for Medicinal Phosphine Compounds
- Phosphine-Based Metal Complexes in Therapeutics
- Bioactivity and Mechanisms of Action
- Phosphines in Drug Delivery Systems
- Antioxidant and Cytoprotective Properties of Phosphines
- Phosphine Compounds in Imaging and Diagnostics
- Toxicological and Pharmacokinetic Profiles
- Computational and Theoretical Approaches
- Clinical and Preclinical Studies
- Future Directions and Emerging Applications
