Introduction
Oxidative stress is a key pathological factor involved in the development and progression of numerous chronic and degenerative diseases, including cancer, cardiovascular disorders, neurodegenerative diseases, metabolic syndromes, and inflammatory conditions. Considerable scientific interest has recently focused on the discovery and characterization of bioactive compounds from natural and synthetic sources capable of modulating oxidative stress and related molecular pathways.
This thematic issue aims to highlight recent advances in the chemical composition, characterization, and biological evaluation of plant extracts, essential oils, and aromatic and medicinal plants, as well as synthetic compounds with potential medical applications. Emphasis will be placed on chromatographic, spectroscopic, and analytical techniques applied to medicinal chemistry and biology. The issue will provide a multidisciplinary platform bringing together medicinal chemistry, natural products chemistry, pharmacology, and biomedical research to promote innovative strategies for combating oxidative stress-related diseases.
Keywords
Oxidative stress, Medicinal chemistry, Plant extracts, Essential oils, Bioactive compounds, Chromatography, Antioxidant activity.
Sub-topics
· Chemical composition and phytochemical profiling of plant extracts and essential oils
· Aromatic and medicinal plants: isolation and characterization of bioactive compounds
· Synthetic bioactive compounds with antioxidant and therapeutic potential
· Chromatographic and spectroscopic techniques (GC-MS, LC-MS, HPLC, NMR) in medicinal chemistry
· Biological activities related to oxidative stress (antioxidant, anti-inflammatory, anticancer, neuroprotective)
· Natural and synthetic compounds targeting oxidative stress-related diseases
