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Innovative Nanocarrier Systems for Tumor Targeting and Therapy

Journal: Current Drug Delivery
Guest editor(s): Dr. Yonghui Liu Nankai University, Tianjin, China | Nankai University, Tianjin, China
Co-Guest Editor(s): Dr. Qingxiang Guo Inner Mongolia University of Technology, Hohhot, China
Submission closes on: 26th October, 2026

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Introduction

In the rapidly evolving field of nanomedicine, innovative nanocarrier systems have emerged as a transformative approach for enhancing tumor targeting and therapeutic efficacy. These advanced systems leverage smart designs—such as stimuli-responsive materials, biomimetic coatings, and multifunctional architectures—to overcome biological barriers, improve tumor accumulation, and minimize off-target toxicity. This Special Issue invites cutting-edge research exploring novel strategies in nanocarrier development. We welcome contributions on, but not limited to, the following themes: 1. Stimuli-Responsive Nanocarriers Light-, pH-, or enzyme-triggered drug release systems for precision therapy. Theranostic platforms integrating imaging and controlled drug delivery. 2. Biomimetic and Biohybrid Nanocarriers Cell membrane-coated nanoparticles for immune evasion and homologous targeting. Extracellular vesicle (EV)-based delivery systems for natural tumor tropism. 3. Multifunctional and Combinatorial Nanosystems Co-delivery of chemotherapeutics, nucleic acids (siRNA/miRNA), and immunomodulators. Nanoplatforms combining photothermal, photodynamic, and chemo-therapies.

Keywords

Nanocarriers, Tumor Targeting, Stimuli-Responsive, Biomimetic, Drug Delivery, Cancer Therapy

Sub-topics

  • Stimuli-responsive carriers (pH/light/enzyme-triggered release)
  • Biomimetic systems (cell membrane coatings, extracellular vesicles)
  • Multifunctional platforms (combined chemo/immuno/phototherapy)

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