[1]
Lim, H.K.; Bae, W.; Lee, H-S.; Jung, J. Anticancer activity of marine sponge Hyrtios sp. extract in human colorectal carcinoma RKO cells with different p53 status. BioMed Res. Int., 2014, 413575.
[2]
Youssef, D.T.; Shaala, L.A.; Asfour, H.Z. Bioactive compounds from the red sea marine sponge Hyrtios Species. Mar. Drugs, 2013, 11(4), 1061-1070.
[3]
Ashour, M.A.; Elkhayat, E.S.; Ebel, R.; Edrada, R.; Proksch, P. Indole alkaloid from the Red Sea sponge Hyrtios Erectus. Arkivoc2007, 15, 225-231. 4. Crews, P.; Bescansa, P. Sesterterpenes from a common marine sponge, Hyrtios erecta. J. Nat. Prod., 1986, 49(6), 1041-1052.
[4]
Crews, P.; Bescansa, P. Sesterterpenes from a common marine sponge, Hyrtios erecta. J. Nat. Prod., 1986, 49(6), 1041-1052.
[5]
Qiu, Y.; Deng, Z.; Pei, Y.; Fu, H.; Li, J.; Proksch, P.; Lin, W. Sesterterpenoids from the Marine Sponge Hyrtios erectus. J. Nat. Prod., 2004, 67(5), 921-924.
[6]
Mollica, A.; Locatelli, M.; Stefanucci, A.; Pinnen, F. Synthesis and bioactivity of secondary metabolites from marine sponges containing dibrominated indolic systems. Molecules, 2012, 17(5), 6083-6099.
[7]
Blunt, J.W.; Copp, B.R.; Hu, W-P.; Munro, M.; Northcote, P.T.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2008, 25(1), 35-94.
[8]
Govek, S.P.; Overman, L.E. Total synthesis of (+)-asperazine. Tetrahedron, 2007, 63(35), 8499-8513.
[9]
Iguchi, K.; Shimada, Y.; Yamada, Y. Hyrtiosal, a new sesterterpenoid with a novel carbon skeleton from the Okinawan marine sponge Hyrtios erectus. J. Org. Chem., 1992, 57(2), 522-524.
[10]
Blunt, J.W.; Copp, B.R.; Hu, W-P.; Munro, M.H.; Northcote, P.T.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2009, 26(2), 170-244.
[11]
Blunt, J.W.; Copp, B.R.; Munro, M.; Northcote, P.T.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2010, 27(2), 165-237.
[12]
Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.H.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2012, 29(2), 144-222.
[13]
Inman, W.D.; Bray, W.M.; Gassner, N.C.; Lokey, R.S.; Tenney, K.; Shen, Y.Y.; TenDyke, K.; Suh, T.; Crews, P. A β-carboline alkaloid from the Papua New Guinea marine sponge Hyrtios reticulatus. J. Nat. Prod., 2009, 73(2), 255-257.
[14]
Momose, R.; Tanaka, N.; Fromont, J.; Kobayashi, J. Hyrtimomines A-C, New Heteroaromatic alkaloids from a sponge Hyrtios sp. Org. Lett., 2013, 15(8), 2010-2013.
[15]
Tanaka, N.; Momose, R.; Takahashi-Nakaguchi, A.; Gonoi, T.; Fromont, J.; Kobayashi, J. Hyrtimomines, indole alkaloids from Okinawan marine sponges Hyrtios spp. Tetrahedron, 2014, 70(4), 832-837.
[16]
Iinuma, Y.; Kozawa, S.; Ishiyama, H.; Tsuda, M.; Fukushi, E.; Kawabata, J.; Fromont, J.; Kobayashi, J. Gesashidine A, a β-carboline alkaloid with an imidazole ring from a thorectidae sponge. J. Nat. Prod., 2005, 68(7), 1109-1110.
[17]
Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.H.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2014, 31(2), 160-258.
[18]
a. Imada, K.; Sakai, E.; Kato, H.; Kawabata, T.; Yoshinaga, S.; Nehira, T.; Terasawa, H.; Tsukamoto, S. Reticulatins A and B and hyrtioreticulin F from the marine sponge Hyrtiosreticulatus. Tetrahedron2013, 69(34), 7051-7055. b. Yamanokuchi, R.; Imada, K.; Miyazaki, M.; Kato, H.; Watanabe, T.; Fujimuro, M.; Saeki, Y.; Yoshinaga, S.; Terasawa, H.; Iwasaki, N., Hyrtioreticulins A-E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus. Bioorg. Med. Chem., 2012, 20(14), 4437-4442.
[19]
Youssef, D.T. Hyrtioerectines A-C, Cytotoxic Alkaloids from the Red Sea Sponge Hyrtios erectus. J. Nat. Prod., 2005, 68(9), 1416-1419.
[20]
Longeon, A.; Copp, B.R.; Quévrain, E.; Roué, M.; Kientz, B.; Cresteil, T.; Petek, S.; Debitus, C.; Bourguet-Kondracki, M-L. Bioactive indole derivatives from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios sp. Mar. Drugs, 2011, 9(5), 879-888.
[21]
Kobayashi, J.; Murayama, T.; Ishibashi, M.; Kosuge, S.; Takamatsu, M.; Ohizumi, Y.; Kobayashi, H.; Ohta, T.; Nozoe, S.; Takuma, S. Hyrtiosins A and B, new indole alkaloids from the Okinawan marine sponge Hyrtios erecta. Tetrahedron, 1990, 46(23), 7699-7702.
[22]
Ciblat, S.; Kim, J.; Stewart, C.A.; Wang, J.; Forgione, P.; Clyne, D.; Paquette, L.A. A modular approach to marine macrolide construction. 4. assembly of c36-c51 and c29-c44 building blocks and evaluation of key coupling reactions targeting spongistatin 1 (Altohyrtin A). Org. Lett., 2007, 9(4), 719-722.
[23]
Paterson, I.; Chen, D.Y-K.; Coster, M.J.; Aceña, J.L.; Bach, J.; Wallace, D.J. The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: Fragment couplings, completion of the synthesis, analogue generation, and biological evaluation. Org. Biomol. Chem., 2005, 3(13), 2431-2440.
[24]
Paterson, I.; Aceña, J.L.; Bach, J.; Chen, D.Y-K.; Coster, M.J. Synthesis, and biological evaluation of spongistatin/altohyrtin analogues: E-ring dehydration and C46 side-chain truncation. Chem. Commun., 2003, 1(4), 462-463.
[25]
Endo, T.; Tsuda, M.; Fromont, J.; Kobayashi, J. Hyrtinadine A, a Bis-indole Alkaloid from a Marine Sponge. J. Nat. Prod., 2007, 70(3), 423-424.
[26]
Tasch, B.O.; Merkul, E.; Müller, T.J. One‐Pot synthesis of diazine‐bridged bisindoles and concise synthesis of the marine alkaloid hyrtinadine A. Eur. J. Org. Chem., 2011, 2011(24), 4532-4535.
[27]
Mosquera, Á.; Riveiros, R.; Sestelo, J.P.; Sarandeses, L.A. Cross-coupling reactions of indium organometallics with 2, 5-dihalopyrimidines: Synthesis of Hyrtinadine A. Org. Lett., 2008, 10(17), 3745-3748.
[28]
Govek, S.P.; Overman, L.E. Total synthesis of Asperazine. J. Am. Chem. Soc., 2001, 123(38), 9468-9469.
[29]
Ito, F.; Shudo, K.; Yamaguchi, K. Total synthesis of (±)-hyrtiazepine. Tetrahedron, 2011, 67(10), 1805-1811.
[30]
Zhang, P.Y.; Wan, S.B.; Ren, S.M.; Jiang, T. First total synthesis of marine alkaloid hyrtiosulawesine. Chin. Chem. Lett., 2010, 21(11), 1307-1309.
[31]
Bergman, J.; Janosik, T.; Johnsson, A-L. Synthesis of hyrtiosin B, a bis-indole alkaloid from the Okinawan marine sponge Hyrtios erecta. Synthesis, 1999, 4, 580-582.
[32]
Garson, O.; Hagemeijer, A.; Sakurai, M.; Reeves, B.; Swansbury, G.; Williams, G.; Alimena, G.; Arthur, D.; Berger, R.; De La Chapelle, A. Cytogenetic studies of 103 patients with acute myelogenous leukemia in relapse. Cancer Genet. Cytogenet., 1989, 40(2), 187-202.
[33]
Haque, M.U.; Rahman, M.A.; Haque, M.A.; Sarker, A.K.; Islam, M.A.U. Antimicrobial and Anticancer Activities of Ethyl Acetate Extract of Co-culture of Streptomyces sp. ANAM-5 and AIAH-10 Isolated From Mangrove Forest of Sundarbans, Bangladesh. J. Appl. Pharm. Sci., 2016, 6(2), 51-55.
[34]
Ding, L.; Ley, T.J.; Larson, D.E.; Miller, C.A.; Koboldt, D.C.; Welch, J.S.; Ritchey, J.K.; Young, M.A.; Lamprecht, T.; McLellan, M.D. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature, 2012, 481(7382), 506-510.
[35]
Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep., 2013, 30(2), 237-323.
[36]
Khokhar, S.; Feng, Y.; Campitelli, M.R.; Ekins, M.G.; Hooper, J.N.; Beattie, K.D.; Sadowski, M.C.; Nelson, C.C.; Davis, R.A. Isolation, structure determination and cytotoxicity studies of tryptophan alkaloids from an Australian marine sponge Hyrtios sp. Bioorg. Med. Chem. Lett., 2014, 24(15), 3329-3332.
[37]
Wu, S-Y.; Sung, P-J.; Chang, Y-L.; Pan, S-L.; Teng, C-M. Heteronemin, a spongean sesterterpene, induces cell apoptosis and autophagy in human renal carcinoma cells. BioMed Res. Int., 2015, 738241.
[38]
Varoglu, M.; Corbett, T.H.; Valeriote, F.A.; Crews, P. Asperazine, a selective cytotoxic alkaloid from a sponge-derived culture of Aspergillus niger. J. Org. Chem., 1997, 62(21), 7078-7079.
[39]
Pettit, G.R.; Tan, R.; Melody, N.; Cichacz, Z.A.; Herald, D.L.; Hoard, M.S.; Pettit, R.K.; Chapuis, J-C. Antineoplastic agents 397: Isolation and structure of sesterstatins 4 and 5 from Hyrtios erecta (The republic of maldives). Bioorg. Med. Chem. Lett., 1998, 8(16), 2093-2098.
[40]
Basabe, P.; Diego, A.; Diez, D.; Marcos, I.S.; Mollinedo, F.; Urones, J.G. Hyrtiosanes from labdanes:(-)-Hyrtiosal from sclareol. Synthesis, 2002, 11, 1523-1529.
[41]
Kobayashi, M.; Aoki, S.; Sakai, H.; Kawazoe, K.; Kihara, N.; Sasaki, T.; Kitagawa, I. Altohyrtin A, a potent anti-tumor macrolide from the Okinawan marine sponge Hyrtios altum. Tetrahedron Lett., 1993, 34(17), 2795-2798.
[42]
Mahidol, C.; Prawat, H.; Sangpetsiripan, S.; Ruchirawat, S. Bioactive scalaranes from the Thai sponge Hyrtios gumminae. J. Nat. Prod., 2009, 72(10), 1870-1874.
[43]
Youssef, D.T.; Yamaki, R.K.; Kelly, M.; Scheuer, P.J. Salmahyrtisol A, a Novel Cytotoxic Sesterterpene from the Red Sea Sponge Hyrtios erecta. J. Nat. Prod., 2002, 65(1), 2-6.
[44]
Gross, A.; McDonnell, J.M.; Korsmeyer, S.J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev., 1999, 13(15), 1899-1911.
[45]
Lavrik, I.N. Systems biology of apoptosis signaling networks. Curr. Opin. Biotechnol., 2010, 21(4), 551-555.
[46]
Baehrecke, E.H. Autophagy: dual roles in life and death? Nat. Rev. Mol. Cell Biol., 2005, 6, 505-510.
[47]
Lockshin, R.A.; Zakeri, Z. Caspase-independent cell deaths. Curr. Opin. Cell Biol., 2002, 14(6), 727-733.
[48]
Kopf, S.; Viola, K.; Atanasov, A.G.; Jarukamjorn, K.; Rarova, L.; Kretschy, N.; Teichmann, M.; Vonach, C.; Saiko, P.; Giessrigl, B. In vitro characterisation of the anti-intravasative properties of the marine product heteronemin. Arch. Toxicol., 2013, 87(10), 1851-1861.
[49]
Schumacher, M.; Cerella, C.; Eifes, S.; Chateauvieux, S.; Morceau, F.; Jaspars, M.; Dicato, M.; Diederich, M. Heteronemin, a spongean sesterterpene, inhibits TNFα-induced NF-κB activation through proteasome inhibition and induces apoptotic cell death. Biochem. Pharmacol., 2010, 79(4), 610-622.
[50]
Kinnula, V.L.; Crapo, J.D. Superoxide dismutases in malignant cells and human tumors. Free Radic. Biol. Med., 2004, 36(6), 718-744.
[51]
Singh, U.; Jialal, I. Oxidative stress, and atherosclerosis. Pathophysiology, 2006, 13(3), 129-142.
[52]
Utkina, N. Antioxidant activityofaromatic alkaloids from the marine sponges Aaptos aaptos and Hyrtios SP. Chem. Nat. Compd., 2009, 45(6), 849-853.
[53]
Xu, W.-H.; Ding, Y.; Jacob, M.R.; Agarwal, A.K.; Clark, A.M.; Ferreira, D.; Liang, Z.-S.; Li, X.-C. Puupehanol, a sesquiterpenedihydroquinone
derivative from the marine sponge Hyrtios sp.
Bioorg. Med. Chem. Lett., 2009, 19 21), 6140-6143.
[54]
Cantón, E.; Pemán, J.; Viudes, A.; Quindós, G.; Gobernado, M.; Espinel-Ingroff, A. Minimum fungicidal concentrations of amphotericin B for bloodstream Candida species. Diagn. Microbiol. Infect. Dis., 2003, 45(3), 203-206.
[55]
Li, X-C.; Jacob, M.R.; Khan, S.I.; Ashfaq, M.K.; Babu, K.S.; Agarwal, A.K.; ElSohly, H.N.; Manly, S.P.; Clark, A.M. Potent in vitro antifungal activities of naturally occurring acetylenic acids. Antimicrob. Agents Chemother., 2008, 52(7), 2442-2448.
[56]
Lee, H-S.; Yoon, K-M.; Han, Y-R.; Lee, K.J.; Chung, S-C.; Kim, T-I.; Lee, S-H.; Shin, J.; Oh, K-B. 5-Hydroxyindole-type alkaloids, as Candida albicans isocitrate lyase inhibitors, from the tropical sponge Hyrtios sp. Bioorg. Med. Chem. Lett., 2009, 19(4), 1051-1053.
[57]
Pettit, R.K.; McAllister, S.C.; Pettit, G.R.; Herald, C.L.; Johnson, J.M.; Cichacz, Z.A. A broad-spectrum antifungal from the marine sponge Hyrtios erecta. Int. J. Antimicrob. Agents, 1998, 9(3), 147-152.
[58]
El Sayed, K.A.; Bartyzel, P.; Shen, X.; Perry, T.L.; Zjawiony, J.K.; Hamann, M.T. Marine natural products as antituberculosis agents. Tetrahedron, 2000, 56(7), 949-953.
[59]
Wonganuchitmeta, S-N.; Yuenyongsawad, S.; Keawpradub, N.; Plubrukarn, A. Antitubercular sesterterpenes from the Thai sponge Brachiaster sp. J. Nat. Prod., 2004, 67(10), 1767-1770.
[60]
Youssef, D.T.; Shaala, L.A.; Emara, S. Antimycobacterial Scalarane-Based Sesterterpenes from the Red Sea Sponge Hyrtios erecta. J. Nat. Prod., 2005, 68(12), 1782-1784.
[61]
Doi, Y.; Shigemori, H.; Ishibashi, M.; Mizobe, F.; Kawashima, A.; Nakaike, S.; Kobayashi, J. New sesterterpenes with nerve growth factor synthesis-stimulating activity from the Okinawan marine sponge Hyrtios sp. Chem. Pharm. Bull., 1993, 41(12), 2190-2191.
[62]
Thoenen, H.; Barde, Y-A. Physiology of nerve growth factor. Physiol. Rev., 1980, 60(4), 1284-1335.
[63]
Aoki, S.; Ye, Y.; Higuchi, K.; Takashima, A.; Tanaka, Y.; Kitagawa, I.; Kobayashi, M. Novel neuronal nitric oxide synthase (nNOS) selective inhibitor, an aplysinopsin-type indole alkaloid, from marine sponge Hyrtios erecta. Chem. Pharm. Bull., 2001, 49(10), 1372-1374.
[64]
Hamann, M.T.; Scheuer, P.J. Cyanopuupehenol, an antiviral metabolite of a sponge of the order Verongida. Tetrahedron Lett., 1991, 32(41), 5671-5672.