Title:Green Chemistry Approach as a Versatile Platform for Nanoparticles with Biomedical Applications
Volume: 7
Issue: 1
Author(s): B. S. Unnikrishnan, Manu M. Joseph, G. U. Preethi, R. Shiji and T. T. Sreelekha
Affiliation:
Keywords:
Biomedical applications, cancer, chitosan, green synthesis, nanoparticles.
Abstract: Nanotechnology plays a prominent role virtually in every field of science and
technology, especially in the drug delivery systems. Nanoparticles (NPs) possess unique
advantages over the existing strategies prevailed in biomedical applications but, they face
certain challenges including its synthesis from expensive synthetic routes and use of toxic
reagents. Till date, most of the approaches focused on the synthesis of NPs from nonbiological
sources and its application is limited due to its toxicity and instability in biological
systems. Biogenic NPs paved a ray of hope in the establishment of a new era with ecofriendly
nanoparticles in medical sciences particularly in drug delivery, bio-imaging and
other therapeutic approaches. The preparation of NPs using biological materials is described
under “green chemistry” approach; which is a philosophy of chemical research and
engineering that encourages the design of products and processes that minimize the use
and generation of hazardous substances through smarter production. Past decade saw a
large number of significant developments with the application of biogenic NPs in the field
of oncology. Various materials of biological origin offer unique promising features to tailor
biogenic NPs with predefined properties. The current review describes about the recent
developments in the synthesis and significance of biogenic NPs in the management of
various clinical abnormalities especially cancer. By drawing diverse toolset for generation
of NPs from inexpensive biological source, this article exploits high impact application of
these NPs in biomedical field.
