Title:New Perspectives in Glioblastoma: Nanoparticles-based Approaches
Volume: 17
Issue: 3
Author(s): Rosa Luciano, Giulia Battafarano, Rossana Saracino, Michela Rossi, Antonio Perrotta, Melania Manco, Maurizio Muraca and Andrea Del Fattore
Affiliation:
Keywords:
Glioblastoma, nanomedicine, nanoparticles, extracellular vesicles.
Abstract: Glioblastoma multiforme represents one of the most aggressive tumor of central nervous
system. Current therapy includes surgery, radiation and chemotherapy. These treatments are rarely
curative and glioma are associated with a poor prognosis. Nanomedicine represents the most innovative
branch of medicine since many studies demonstrated great advantage in the diagnosis and therapy
of several diseases. In this review we will summarize the results obtained by the use of nanoparticles
and extracellular vesicles in glioblastoma. A great interest is raising from these studies that underlined
the efficacy and specificity of this treatment for glioma, reducing side-effects associated with
conventional therapies.