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Current Topics in Medicinal Chemistry


ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines

Author(s): K. S. Jain, N. Arya, N. N. Inamdar, P. B. Auti, S. A. Unawane, H. H. Puranik, M. S. Sanap, A. D. Inamke, V. J. Mahale, C. S. Prajapati and C. J. Shishoo

Volume 16, Issue 28, 2016

Page: [3133 - 3174] Pages: 42

DOI: 10.2174/1568026616666160609100410

Price: $65


This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures, have been covered. The chemistry and synthesis of pyrimidines have also been briefly discussed.

Keywords: Bioactive Heterocycles, Pyrimidines, Condensed Pyrimidines, Biological significance, Medicinal significance, Synthesis.

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