Title:QT Prolongation and Anticancer Drugs: Is it a Cardiologist’s Worry? The Oncologist’s Point of View
Volume: 11
Issue: 3
Author(s): Francesca Aroldi, Tiziana Prochilo, Elena Bonini and Alberto Zaniboni
Affiliation:
Keywords:
Adverse cardiac events, cancer, QT prolongation, through QT study, torsade de point.
Abstract: Currently, many novel therapies are available for physicians treating cancer; some of them are associated with
adverse cardiac events. One of the most worrisome cardiac event is QT prolongation, which is a risk factor for developing
the potentially fatal torsade de pointe. Many classes of drugs, both anticancer and concomitant agents, are involved in this
issue. We report a review of old and new commonly used agents with torsadogenic potential.