Title:An update on Anti-inflammatory Compounds: A Review
Volume: 14
Issue: 2
Author(s): Ashwani Kumar Dhingra, Bhawna Chopra, Rameshwar Dass and Sanjeev Kumar Mittal
Affiliation:
Keywords:
Inflammation, NSAIDs, ImSAIDS, glucocorticoids, SEGRA, resolvins.
Abstract: Inflammation is a protective attempt by the organism to remove the injurious
stimuli and to initiate the healing process. Also, it has been reported to be associated with
the onset of various cancers. An effective anti-inflammatory drug should be able to inhibit
the development of inflammation without interfering in normal homeostasis. Current approaches to overcome
the inflammation include the use of immune selective anti-inflammatory derivatives, selective glucocorticoid
receptor agonist, resolvins and protectins and TNF inhibitors. A number of herbal drugs have been identified
in the past that can target inflammatory cytokines. This review mainly focuses on the newer molecules to
combat the inflammation and also emphasise on various studies carried out in the past. Thus, the high prevalence
of inflammation obliges the development of new drugs; therefore, a safe and efficient drug molecule to
confer protection against inflammation is urgently needed.
