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Endocrine, Metabolic & Immune Disorders - Drug Targets


ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

Use Of External Intrathecal Infusion Pumps In The Management Of Septic Complications: A Case Report

Author(s): Riccardo Marvulli, Pierpaolo Chiumarulo, Mattia Nisi, Laura Barulli, Gianfranco Megna, Fiore Pietro, Giancarlo Ianieri and Marisa Megna

Volume 15, Issue 4, 2015

Page: [293 - 296] Pages: 4

DOI: 10.2174/1871530315666150506124127

Price: $65


Spasticity is a motor disorder with an increased muscle tone, typically associated with spasms, weakness and lack of coordination. It is an invalidating and debilitating pathology, characterized by pain, limited autonomy in activities of daily living, development of severe lesions. Spasticity can be adequately treated with physiotherapy, muscle relaxants drugs or topical treatment with botulinic toxin type A. Intrathecal baclofen therapy is very effective in the treatment of severe and generalized spasticity. Sometimes, soft tissues adjacent to the implant intrathecal infusion become infected; removing intrathecal infusion and systemic antibiotic therapy are best solution for clinical cure. However, removing intrathecal baclofen therapy could increase muscle spasticity with enhancement of pain and clonus that can worsen quality of life. In this study, we evaluated clinical improvement after complete healing of the septic focus and implantation of a new infuser

Keywords: Antibiotic therapy, baclofen, clonus, infection, intrathecal infusion, spasticity.

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