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CNS & Neurological Disorders - Drug Targets


ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Deep Brain Stimulation: A New Treatment in Mood and Anxiety Disorders

Author(s): Bruna Velasques, Claudia Diniz, Silmar Teixeira, Consuelo Cartier, Caroline Peressutti, Farmy Silva, Marcele de Carvalho, Aline Novaes, Juliana Bittencourt, Antonio Egidio Nardi, Elie Cheniaux, Luis Basile, Mauricio Cagy, Roberto Piedade and Pedro Ribeiro

Volume 13, Issue 6, 2014

Page: [961 - 971] Pages: 11

DOI: 10.2174/1871527313666140612122929

Price: $65


This article considered already existing studies about Deep Brain Stimulation in Mood and Anxiety Disorders. In particular, articles regarding Obsessive-Compulsive Disorder and Major Depression were mostly analyzed, due to the lack of researches about other types of Mood and Anxiety Disorders. We have concentrated on the target areas where Deep Brain Stimulation was most commonly applied, and on the effects this measure had on treatment-refractory patients. The obtained results showed that the stimulation of the: nucleus accumbens, subgenual cingulate cortex and ventral capsule/ventral striatum, has a positive influence on the development of the disorders investigated, sometimes showing the complete remission of the symptoms. Although Deep Brain Stimulation was overall found to be a promising and safe treatment for Mood and Anxiety Disorders, there are not enough studies proving its efficacy in wide samples and in the presence of more complex variables.

Keywords: Anxiety disorder, deep brain stimulation, depression, obsessive compulsive disorder.

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