Title:Anomalous Vascular Supply of Bronchial Circulation in Cystic Fibrosis Patients with Massive Hemoptysis
Volume: 9
Issue: 6
Author(s): Rebanta Chakraborty, Alexander E. Trebelev, Brian Bianco, William O’Connell, Michael J. Stephen and Jeffrey B. Hoag
Affiliation:
Keywords:
Bronchial artery embolization, cystic fibrosis, hemoptysis.
Abstract: Background: Hemoptysis occurs commonly in patients with Cystic Fibrosis, and massive bleeding requiring
emergent intervention occurs in a subset. Bronchial artery embolization (BAE) is recommended in clinically unstable CF
patients with massive hemoptysis (MH); however, no consensus exists regarding selective versus extensive embolization,
and recommendations of targets are scant.
Objective: We sought to characterize the frequency of abnormal bronchial circulation in MH in CF in order to suggest
interventional approach for BAE.
Methods: A retrospective chart review of BAE for MH was performed. Characterization of angiography was described,
and CF and non-CF patients were compared.
Results: 10 CF and 7 non-CF patients with MH were identified. Dilated, tortuous bronchial vessels were ubiquitous in CF,
and 70% had non-bronchial collaterals. CF patients required more extensive BAE and 50% had >1 collateral. Anomalous
supplies were described, and a correlation between the volume of hemoptysis and number of collaterals was determined.
Conclusion: Anomalous bronchial arteries origin and supply should be suspected in CF. Angiographic approach in CF
should include arch aortograms to demonstrate entire supply of the bronchial arterial field.
