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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Aspergillus – Classification and Antifungal Susceptibilities

Author(s): Walter Buzina

Volume 19, Issue 20, 2013

Page: [3615 - 3628] Pages: 14

DOI: 10.2174/1381612811319200005

Price: $65


Aspergillus is one of the most important fungal genera for the man, for its industrial use, its ability to spoil food and not least its medical impact as cause of a variety of diseases. Currently hundreds of species of Aspergillus are known; nearly fifty of them are able to cause infections in humans and animals. Recently, the genus Aspergillus is subdivided into 8 subgenera and 22 sections. The spectrum of diseases caused by Aspergillus species varies from superficial cutaneous to invasive and systemic infections. All species of Aspergillus investigated so far are resistant against the antifungals fluconazole and 5-fluorocytosine, the range of susceptibilities to currently available antifungals is discussed in this paper.

Keywords: Aspergillus, susceptibility, antifungals, antimycotic drugs.

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