Title:Principles and Applications of Diffuse Optical Imaging for the Brain
Volume: 8
Author(s): Michele Desjardins, Philippe Pouliot and Frederic Lesage
Affiliation:
Keywords:
Diffuse optical imaging, diffuse optical tomography, near-infrared spectroscopy
Abstract: Diffuse optical imaging (DOI) of the brain has emerged as a new neuroimaging technique that is seeing growing
applications in brain research. The technique’s simplicity, lower cost and applicability to children have contributed to
its popularity. However, the translation of DOI to clinically relevant scenarios has lagged. Poor quantification of local
hemodynamic changes based on optical signals remains a major hurdle and significant efforts are still being pursued to
better understand how to recover accurate images of functional activation and generate statistical maps, and to identify the
limitations of DOI. This paper reviews the underlying principles of brain DOI and applications that may find a niche in
the clinic.
