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Current Drug Abuse Reviews


ISSN (Print): 1874-4737
ISSN (Online): 1874-4745

Substance Abuse and Movement Disorders: Complex Interactions and Comorbidities

Author(s): Andres Deik, Rachel Saunders-Pullman and Marta San Luciano

Volume 5, Issue 3, 2012

Page: [243 - 253] Pages: 11

DOI: 10.2174/1874473711205030243

Price: $65


The relationship between movement disorders and substance abuse, which we previously reviewed, is updated. We examine these relationships bidirectionally with focus on drugs of abuse that are known to cause movement disorders, as well as primary movement disorders that are associated with use and abuse of alcohol and dopaminergic medications. First, we review the movement disorders that may develop from the acute use or withdrawal of frequent drugs of abuse, including alcohol, cocaine, heroin, amphetamine and methcathinone. We then comment on the interaction between alcoholism and alcohol-responsive movement disorders, such as essential tremor and myoclonus-dystonia. Lastly, we discuss the potential for abuse of antiparkinsonian dopaminergic agents in patients with Parkinson’s disease (PD).

Keywords: Movement disorders, Parkinsonism, dystonia, chorea, drugs, tremor, tics, alcohol, substance abuse, cocaine.

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