Title: Characterization of Adipose-Derived Stem Cells: An Update
Volume: 5
Issue: 2
Author(s): Alexander M. Bailey, Sahil Kapur and Adam J. Katz
Affiliation:
Keywords:
Characterization, isolation, donor variability, expansion, adipose-derived stem cell, stromal cell
Abstract: Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.
