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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Efficacy of Fluoroquinolones Against Pathogenic Oral Bacteria

Author(s): V. Nunez Otero, J. Limeres Posse, I. Tomas Carmona and P. Diz Dios

Volume 9, Issue 10, 2009

Page: [1147 - 1158] Pages: 12

DOI: 10.2174/138955709789055243

Price: $65


This article reviews the characteristics of the main fluoroquinolones used in dentistry (ciprofloxacin, levofloxacin and moxifloxacin), including pharmacokinetic/ pharmacodynamic parameters, susceptibility profiles of oral bacteria and clinical trials on their efficacy in dental practice. It seems that some of these antibiotics might represent a safe alternative in patients with allergy, intolerance, or lack of response to beta-lactams.

Keywords: Antimicrobial susceptibility, ciprofloxacin, fluoroquinolones, focal infection, levofloxacin, moxifloxacin, oral infection, oral pathogens

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