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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Forms of Iron Binding in the Cells and the Chemical Features of Chelation Therapy

Author(s): S. Puntarulo and M. Galleano

Volume 9, Issue 9, 2009

Page: [1136 - 1146] Pages: 11

DOI: 10.2174/138955709788922674

Price: $65


Iron is essential for human life, however it can be toxic through Fe ability to generate oxygen-derived radicals. This work reviews the main features of Fe binding in the cell and its association to these processes. The chemical nature of the Fe extracted by chelation therapy in pathophysiological situations is also analyzed.

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