Preface

The title "Artificial Intelligence and In Silico Strategies for Novel Target Identification in Alzheimer's Disease" emphasizes the use of Artificial intelligence (AI) and advanced in silico methods to address Alzheimer's disease (AD), a neurodegenerative condition that currently has few effective treatments. AI and insilico methods, including molecular modeling, simulations, are ...read more

Enzyme-targeted drug discovery represents one of the most relevant strategies in pharmaceutical development, owing to the high specificity, selectivity, and central role of enzymes in the regulation of biological processes. This proposed issue aims to compile key information on the current landscape of enzyme-targeted drug discovery, with emphasis on the ...read more

Advancements in computational science and high-performance computing have made computer-aided drug design (CADD) a fundamental approach in modern drug discovery. CADD enables precise molecular-level analysis of target binding sites and interaction mechanisms, expediting the identification and refinement of drug candidates. It comprises structure-based drug design (SBDD), enhanced by crystallography and ...read more

The use of several compounds has been the subject of increasing interest in phytochemistry, biochemistry and other fields of research at the chemistry-biology-ecosystems interface. In spite of the continued search for new anticancer drugs, cancer remains a leading cause of death. Cancer mortalities are expected to increase to 12.9 million, ...read more