Title: Anticonvulsant Activity Of Benzylamides Of Some Amino Acids And Heterocyclic Acids
Volume: 10
Issue: 5
Author(s): Ryszard Paruszewski, Marzanna Strupinska, Grazyna Rostafinska-Suchar and James P. Stables
Affiliation:
Keywords:
anticonvulsants, n-methyle-glu, n-methyl-asp derivatives, heterocyclic acid derivaties
Abstract: A series of new potential anticonvulsants have been synthesized. They are N-methyl benzylamides of N-methyl Asp and N-methyl Glu (R and S), benzylamides of some heterocyclic acids and their Noxides and benzylamides of two heteroalicyclic acids. The obtained compounds were evaluated in the Anticonvulsant Screening Project (ASP) of Antiepileptic Drug Development Program (ADDP) of NIH.