Title: Urocortin: Cardiovascular Actions and Therapeutic Implications
Volume: 1
Issue: 2
Author(s): M. T. Rademaker
Affiliation:
Keywords:
urocortin, heart, vasculature, vasodilation, inotropism, cardioprotection
Abstract: Urocortin, expressed throughout the heart and vasculature, has potent effects on the cardiovascular system including vasodilation, increases in cardiac contractility and coronary blood flow, and protection of the myocardium against ischemia / reperfusion damage. This range of actions suggests urocortin has therapeutic potential in states of cardiac dysfunction and injury.