Regulatory T-Cells: Immunomodulators in Health and Disease

The title "Artificial Intelligence and In Silico Strategies for Novel Target Identification in Alzheimer's Disease" emphasizes the use of Artificial intelligence (AI) and advanced in silico methods to address Alzheimer's disease (AD), a neurodegenerative condition that currently has few effective treatments. AI and insilico methods, including molecular modeling, simulations, are ...read more

Phytochemicals are naturally occurring bioactive molecules widely present in plant-derived foods and medicinal plants. Accumulating evidence has demonstrated their protective effects against a wide range of metabolic disorders, such as type 2 diabetes, insulin resistance, and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), as well as cardiovascular disease, pulmonary fibrosis, and ...read more

Enzyme-targeted drug discovery represents one of the most relevant strategies in pharmaceutical development, owing to the high specificity, selectivity, and central role of enzymes in the regulation of biological processes. This proposed issue aims to compile key information on the current landscape of enzyme-targeted drug discovery, with emphasis on the ...read more

Advancements in computational science and high-performance computing have made computer-aided drug design (CADD) a fundamental approach in modern drug discovery. CADD enables precise molecular-level analysis of target binding sites and interaction mechanisms, expediting the identification and refinement of drug candidates. It comprises structure-based drug design (SBDD), enhanced by crystallography and ...read more