Title: Epidemiology and Prevention of Viral Infections in Patients with Hematologic Malignancies
Volume: 11
Issue: 1
Author(s): Michael Angarone
Affiliation:
Keywords:
Cytomegalovirus, herpes simplex virus, varicella zoster virus, influenza virus, hepatitis B virus, hematologic malignancy, anti-viral agents, vaccines, prophylaxis, T-cell dysfunction, lymphoid derived leukemia, mye-loid derived leukemia, chronic lymphocytic leukemia, fludarabine, monoclonal antibodies, pneumonitis, alemtuzumab, oral acyclovir
Abstract: Viral infections are some of the most frequent complications in patients with hematologic malignancies are viral infections. Infections caused by cytomegalovirus, herpes simplex virus, varicella zoster virus, hepatitis B virus and influenza virus are associated with high morbidity and mortality in this vulnerable population. Fortunately, a growing number of antiviral medications and vaccines are allowing for more effective prophylaxis against these pathogens. This article reviews the epidemiology and prophylactic strategies available for these opportunistic viral pathogens.
