Generic placeholder image

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry


ISSN (Print): 1871-5230
ISSN (Online): 1875-614X

Pharmacogenomics – Implications in the Development of HIV-Associated Brain Disease

Author(s): Thorsten Nolting and Gabriele Arendt

Volume 8, Issue 2, 2009

Page: [164 - 168] Pages: 5

DOI: 10.2174/187152309789152101

Price: $65


Pharmacogenomics is a relatively new field in HIV-research, especially when neurological issues are concerned. Influence of polymorphisms in CYP3A4, CYP2B6, CYP2D6, ABCB1, ABCG2, ABCC4, SLC22, SLC28, SLC29 and MMP9-genes on pharmacokinetic data is discussed in the article. Due to the lack of published studies, but promising results in the few existing publications, scientists should be encouraged to integrate neurological aspects in pharmacogenomics research.

Keywords: HIV, CNS, pharmacogenomics, pharmacogenetics, MMP9, SLC, ABC-transporter, cytochrome

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy