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Recent Advances in Anti-Infective Drug Discovery

Recent Advances in Anti-Infective Drug Discovery

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ISSN (Print): 2772-4344
ISSN (Online): 2772-4352

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Review Article

Nature’s Remedy: A Comprehensive Review Exploring Herbal Treatments and Natural Approaches for Preventing Acne Vulgaris

Author(s): Muskan Shingari, Anjali Sharma* and Vishnu Mittal

Volume 21, Issue 1, 2026

Published on: 14 July, 2025

Page: [1 - 26] Pages: 26

DOI: 10.2174/0127724344345143250709035643

Price: $65

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Abstract

Background: Acne vulgaris is a prevailing inflammatory condition of the skin affecting areas with dense sebaceous glands, like the upper back, chest, face, and arms. It impacts approximately 85% of Americans aged 12 to 25, which can persist into adulthood. The condition is identified with pustules, comedones, papules, and nodules, comprising psychological and social effects comparable to chronic diseases like asthma.

Objectives: This study explores the potential of herbal treatments as alternatives to conventional allopathic therapies for acne vulgaris, aiming to address underlying causes with fewer side effects.

Methods: A comprehensive literature review was conducted, examining clinical studies, traditional medicinal sources, and recent research on various herbs, including Melaleuca alternifolia (tea tree), Curcuma longa (turmeric), Azadirachta indica (neem), Aloe barbadensis (aloe vera), Camellia sinensis (green tea), Salvia rosmarinus (rosemary), and Amaranthushypochondriacus Linn (amaranths). Both topical and internal applications were considered, with a focus on topical treatments for ease of use. The databases PubMed, Web of Science, Cochrane Library, Google Scholar, ResearchGate, and ScienceDirect were the main sources of the data and content included in this review article. This helped to preserve transparency and increased the credibility of this review article.

Results: Herbal medicines are gaining traction due to their minimal adverse effects and holistic approach. This study highlights promising results from several herbs in reducing acne symptoms and improving skin health, emphasizing the need for further clinical trials to substantiate these findings.

Conclusion: Herbal therapies offer a viable alternative for managing acne vulgaris, potentially providing a holistic solution beyond symptomatic relief. Continued research is important to understand their effectiveness and mechanisms of action fully.

Keywords: Acne vulgaris, propionibacterium acnes, Melaleuca alternifolia, Azadirachtaindica, Curcuma longa, Aloe barbadensis, Camellia sinensis, Salvia rosmarinus.

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Graphical Abstract

Graphical abstract illustrating key findings of the study

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