Endocrine, Metabolic & Immune Disorders - Drug Targets

Endocrine, Metabolic & Immune Disorders - Drug Targets

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ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

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Case Report

A Rare Case of Ischial Tubercle Pressure Sore with Secondary Periperineal Necrotizing Fasciitis

Author(s): Peiqi Wang, Yiyang Liu*orcid of author, Junhua Wang, Qiaofeng Guo and Xiang Wang

Volume 26, 2026

Published on: 04 April, 2025

Article ID: e18715303385272

Pages: 5

DOI: 10.2174/0118715303385272250320042418

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Abstract

Background: Perineal necrotizing fasciitis, or Fournier's gangrene, is a rare but rapidly progressing condition characterized by fascial necrosis. It is a severe, potentially life-threatening infection requiring prompt diagnosis and standardized treatment to optimize patient outcomes.

Case Presentation: A 48-year-old woman with poorly controlled type 2 diabetes developed necrotizing fasciitis of the right perineum secondary to an ischial tuberosity pressure ulcer. She had a prior spinal cord injury resulting in sensory dysfunction in the lower limbs, which masked significant pain. Management included surgical debridement, open wound care, antimicrobial therapy, and a free skin graft for wound closure.

Conclusion: Effective treatment of necrotizing fasciitis relies on aggressive debridement and appropriate antimicrobial therapy. This case highlights the importance of early recognition and intervention to improve clinical diagnostic and management strategies.

Keywords: Pressure ulcer, ischial tuberosity, perineum, necrotizing fasciitis, surgical debridement, antimicrobial therapy.

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